Title a extra iconic duo than Jane Fonda and Lily Tomlin. I dare you.
Sandra Oh and Ellen Pompeo as Cristina and Meredith on Grey’s Anatomy (2005–most up-to-date)
Regina Hall and Anna Faris as Brenda and Cindy in Scary Film 2 (2001)
Julie Andrews and Anne Hathaway as Queen Clarisse and Mia Thermopolis in The Princess Diaries (2001)
Tisha Campbell and Tichina Arnold as Gina and Pam in Martin (1992–1997)
Margot Robbie and Kate McKinnon as Kayla and Jess in Bombshell (2019)
Shay Mitchell and Bianca Lawson as Emily and Maya on Magnificent Limited Liars (2010–2017)
Jane Fonda and Lily Tomlin as Grace and Frankie on Grace and Frankie (2015–most up-to-date)
Tatiana Maslany and Évelyne Brochu as Cosima and Delphine on Orphan Sunless (2013–2017)
Mary-Louise Parker and Mary Stuart Masterson as Ruth and Idgie in Fried Green Tomatoes (1991)
Angela Bassett and Whoopi Goldberg as Stella and Delilah in How Stella Got Her Groove Reduction (1998)
Melissa Fumero and Stephanie Beatriz as Amy and Rosa on Brooklyn 9-9 (2013–most up-to-date)
Jamie Clayton and Freema Agyeman as Nomi and Amanita on Sense8 (2015–2018)
Mira Sorvino and Lisa Kudrow as Romy and Michele in Romy and Michele’s High College Reunion (1997)
Jodie Comer and Sandra Oh as Villanelle and Eve on Killing Eve (2018–most up-to-date)
Cate Blanchett and Rooney Mara as Carol and Therese in Carol (2015)
Whitney Houston and Brandy as Fairy Godmother and Cinderella in Rodgers & Hammerstein’s Cinderella (1997)
Maya Erskine and Anna Konkle as Maya and Anna in PEN15 (2019–most up-to-date)
Kaitlyn Dever and Diana Silvers as Amy and Hope in Booksmart (2019)
Amy Poehler and Rashida Jones as Leslie and Anne on Parks and Game (2009–2015)
Sanaa Lathan and Alfre Woodard as Monica and Camille in Enjoy & Basketball (2000)
And Naya Rivera and Heather Morris as Santana and Brittany on Glee (2009–2015)
Reward: Submissions were edited for length and/or readability.
Which female actors fabricate you deem had the finest onscreen chemistry in a movie or TV stamp? Remark us in the comments under!